Vol. 7, Issue 2, Part B (2025)

Erectile dysfunction and lower urinary tract symptoms are prevalent urological conditions negatively affecting men's quality of life, with a well-established correlation in older men. However, limited data exist regarding this association in younger males. This study aimed to evaluate the relationship between uroflowmetry parameters and erectile dysfunction in men under 45 years, considering their potential role as early markers for erectile dysfunction. A prospective observational study was conducted involving 33 men younger than 45 years presenting with erectile dysfunction at a tertiary care urology center from November 2023 to January 2025. Participants underwent comprehensive clinical assessment including uroflowmetry measurements, penile Doppler evaluation and erectile function using the International Index of Erectile Function-5 questionnaire. Statistical analyses examined correlations between International Index of Erectile Function-5 scores, uroflowmetry parameters, metabolic profiles and International Prostate Symptom Score. The mean participant age was 33.7 years. Erectile dysfunction severity was predominantly mild to moderate and moderate with fewer cases of severe and mild dysfunction. Statistically significant positive correlations existed between erectile function scores and maximum flow rate and average flow rate. Voided volume also correlated strongly with maximum and average flow rates. Negative correlations were observed between International Prostate Symptom Score and urinary flow rates. No significant associations were found between erectile function and testosterone or lipid parameters. Reduced urinary flow rates, especially maximum and average flow rates, are significantly associated with erectile dysfunction severity in young men. Uroflowmetry offers a valuable, non-invasive tool for early detection of erectile dysfunction, reflecting shared mechanisms between lower urinary tract symptoms and erectile dysfunction.